Seed VC · San Francisco

Spero VC

Active

What they invest in

A boutique venture firm for purpose-led companies where mission-driven founders find passionate partners to support their daily pursuit of purpose. Tomorrow's most valuable companies will tackle today's most meaningful challenges.

Who they back

Climate TechSeries ASeries B

Business models

saas_b2b, saas_b2c, marketplace, hardware, deeptech_ip, biotech_therapeutics

Customer segments

Enterprise, Mid-market, SMB, Consumer, Healthcare providers, Utilities

Geography

US

Recent investments

  • Twelve (e-fuel production)
  • Runway (no-code AI platform)
  • SafeTraces (real-time location intelligence for hospital safety)

+ 3 more deals. Score your deck to see the full investment history.

The people who write checks

6 partners on file at Spero VC, with the firm's email pattern for cold outreach. Score your deck (free, 30 seconds) to unlock direct contact for this firm and 47,000+ others.

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Why this firm matters for fundraising founders

Spero VC writes first institutional checks where the founder + early product matter more than traction. The seed market is the most dispersed segment of venture; matching to thesis (sector, stage, geography) is where most cold outreach succeeds or fails. VC Boom tracks Spero VC alongside 47,000+ other active investors, ranked weekly by recent-deal momentum, sector concentration, and partner activity.

At a glance

Portfolio last checked
Oct 12, 2026
Website
www.spero.vc ↗

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